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NSTI type-specific responses in the host were uncovered. In this study, we built interactomes at both the population and individual levels consisting of host-pathogen interactions inferred from dual RNA-Seq gene transcriptomic profiles of the biopsies from NSTI patients.

However, the underlying pathogenic mechanisms in this heterogeneous group remain elusive. These infections are rare and are associated with high mortality rates. Purchase another subscription from our Online Store.Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial infection).

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